US FDA approved new medicine odactra that contains allergen extract as an active ingredient. It is administered via sublingual route to treat allergic rhinitis with or without eye inflammation. This drug is suitable for people having age between 18years to 65years. Allergic rhinitis is very problem in among all populations without regard to age, gender and physical health. In some areas dust mite is the leading cause of allergic rhinitis found in the house dust, under mattress or carpets, inside the wooden material and in bed sheets. Their tiny structure allow them to hide easily around rough wooden corners, doors or anywhere they found dust.
Allergic rhinitis is basically inflammation and irritation inside the nasal passage due to inflammatory response triggered by inflammatory mediators like histamine etc. Basic mechanism of action by which odactra reduces this inflammation and irritation is desensitization to hose dust mite allergens. It is some kind of immunotherapy in which desensitization is carried out against the causative allergen. After the desensitization process patient becomes non-reactive or less reactive (hypo-allergic) to specific allergen.
Odactra Side effectsAccording to data received from clinical trails this drug may cause life threatening allergic reactions so, it's first dose must be administered under the supervision of a health care professional. According to FDA, product literature includes a boxed warning of severe allergic reactions can occur. Some other
mild to moderate kind of side effects are
- Itching in the ears and mouth
- Swelling of the lips and tongue
- Mucousal irritation
- Skin allergy
- Mild fever