Eucrisa/crisaborole Cost, Side effects, Dosage, Uses for Eczema

Read about Eucrisa/crisaborole Cost, Side effects, Dosage, Uses for Eczema. Eucrisa is manufactured by Palo Alto, California-based Anacor Pharmaceuticals, Inc.

U.S FDA approved new drug Eucrisa that contains crisaborole as topical dosage form  (ointment) for the treatment of eczema ( atopic dermatitis) in patients having age 2 years or more. Eczema. Eczema or atopic dermatitis is a common skin disorder among all populations. It is intense form of skin disorder with an inflammatory response that requires long-term management or sometimes life time management in advance stages.

Exact underlying cause of eczema is not fully understood that triggers inflammatory response. It is proposed that genetic predisposition, environmental factors and immunogenic response play key role in the parthenogenesis of eczema. Most common symptoms of eczema include dry and red scaly appearance of affected area of skin with intense itching. Scratching may cause skin thickness along with swelling that prolongs the duration of therapy.

Main mechanism of Eucrisa/crisaborole is inhibition of  phosphodiesterase-4 that causes inflammation by triggering the release of certain inflammatory mediators like interleukin-12(IL-12), bradykinins, cytokinins and tumor necrosis factor (TNFα). As name indicates that it contains boron that penetrates readily and rapidly into skin is essential for its binding activity.

Eucrisa/crisaborole Cost, Side effects, Dosage, Uses for Eczema

Eucrisa/crisaborole Side effects

According to clinical data provided by health authorities following side effects were documented during clinical trials

  • Hypersensitivity reactions
  • Burning sensation
  • Sting like feeling
  • Mild pain during application

Eucrisa/crisaborole Uses or Prescribing information

U.S FDA approved only topical form of Eucrisa/crisaborole for the treatment eczema ( atopic dermatitis). Clinical data suggests that it should be applied two times a day to get better results. Eucrisa/crisaborole should not be used in patients having age less than 2 years.

Eucrisa/crisaborole Dosage

Eucrisa/crisaborole is manufacturing in the form of ointment with potency of 2%. Normally it should be applied in the form of thin layer topically to affected area twice a day. It should be used in case of mild to moderate kind of atopic dermatitis. It should not be used in children having age less than 2 years.

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